Sioux County, Nebraska
Sioux County is a county in the U.S. state of Nebraska. As of the 2020 census, the population was 1,135, and was estimated to be 1,188 in 2025. The county seat and the largest village is Harrison.
Sioux County is included in the Scottsbluff, NE micropolitan area.
In the Nebraska license plate system, Sioux County was represented by the prefix "80" (as it had the 80th-largest number of vehicles registered in the state when the license plate system was established in 1922).